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Identification of the human cytochrome P450 isoforms mediating in vitro N-dealkylation of perphenazine
AIMS: To identify the human cytochrome P450 (CYP) isoforms mediating the N-dealkylation of the antipsychotic drug perphenazine in vitro and estimate the relative contributions of the CYP isoforms involved. METHODS: cDNA-expressed CYP isoforms were used to identify the isoforms that are able to media...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2000
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2015011/ https://ncbi.nlm.nih.gov/pubmed/11136295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00298.x |
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