Comparison of the neurokinin-1 antagonist GR205171, alone and in combination with the 5-HT(3) antagonist ondansetron, hyoscine and placebo in the prevention of motion-induced nausea in man

AIMS: In man a neurokinin-1 (NK(1)) receptor antagonist has previously been shown to be ineffective in the prevention of motion-induced nausea. The antiemetic efficacy of NK(1) receptor antagonists against chemotherapy-induced emesis is, however, enhanced when combined with a 5-HT(3) receptor antago...

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Detalles Bibliográficos
Main Authors: Reid, K, Palmer, J L, Wright, R J, Clemes, S A, Troakes, C, Somal, H S, House, F, Stott, J R R
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2000
Assuntos:
Short Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014963/
https://ncbi.nlm.nih.gov/pubmed/10886120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00221.x
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