Photoinduced covalent binding of frusemide and frusemide glucuronide to human serum albumin

AIMS: To study reaction of photoactivated frusemide (F) and F glucuronide (Fgnd metabolite) with human serum albumin in order to find a clue to clarify a mechanism of phototoxic blisters from high frusemide dosage. METHODS: F was exposed to light in the presence of human serum albumin (HSA). HSA tre...

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Bibliographic Details
Main Authors: Mizuma, Takashi, McDonagh, Antony F, Lin, Emil T, Benet, Leslie Z
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 1999
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014883/
https://ncbi.nlm.nih.gov/pubmed/10383564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00970.x
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