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Pharmacokinetic and pharmacodynamic characterization of OROS® and immediate-release amitriptyline
AIMS: To characterize the pharmacokinetics of amitriptyline and its metabolite nortriptyline following OROS® and IR treatments, and to correlate them with anticholinergic side-effects. METHODS: The pharmacokinetics and safety of amitriptyline following administration of an osmotic controlled release...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
1999
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014871/ https://ncbi.nlm.nih.gov/pubmed/10383563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00973.x |
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