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Reciprocal regulation of human soluble and particulate guanylate cyclases in vivo

BACKGROUND & PURPOSE: We demonstrated previously that reciprocal regulation of soluble (sGC) and particulate (pGC) guanylate cyclases by NO and natriuretic peptides coordinates cyclic cGMP-mediated vasodilatation in vitro. Herein, we investigated whether such an interaction contributes to vascul...

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Détails bibliographiques
Auteurs principaux: Madhani, M, Okorie, M, Hobbs, A J, MacAllister, R J
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014653/
https://ncbi.nlm.nih.gov/pubmed/17016498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706920
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