No proarrhythmic properties of the antibiotics Moxifloxacin or Azithromycin in anaesthetized dogs with chronic-AV block

BACKGROUND & PURPOSE: The therapeutically available quinolone antibiotic moxifloxacin has been used as a positive control for prolonging the QT interval in both clinical and non-clinical studies designed to assess the potential of new drugs to delay cardiac repolarization. Despite moxifloxacin p...

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Detalhes bibliográficos
Main Authors: Thomsen, M B, Beekman, J D M, Attevelt, N J M, Takahara, A, Sugiyama, A, Chiba, K, Vos, M A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014631/
https://ncbi.nlm.nih.gov/pubmed/17088870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706900
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