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Simultaneous fitting of R- and S-ibuprofen plasma concentrations after oral administration of the racemate

AIMS: To assess the pharmacokinetic equivalence of two different formulations of ibuprofen lysinate with special focus on the expected effects. METHODS: Sixteen healthy volunteers received cross-over ibuprofen lysinate as either one tablet of 400 mg (‘test’) or two tablets of 200 mg (‘reference’). I...

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Detaylı Bibliyografya
Asıl Yazarlar: Lötsch, Jörn, Muth-Selbach, Uta, Tegeder, Irmgard, Brune, Kay, Geisslinger, Gerd
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014594/
https://ncbi.nlm.nih.gov/pubmed/11678782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2001.01451.x
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