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Distribution of R- and S-methadone into human milk during multiple, medium to high oral dosing

AIMS: To measure the interdose milk to plasma ratio (M/P) of R- and S-methadone during multiple dosing in lactating mothers taking medium to high doses of methadone (> 40 mg daily), and to assess likely infant exposure. METHODS: Eight mother/child pairs were studied, initially during their postpa...

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Detalhes bibliográficos
Main Authors: Begg, Evan J, Malpas, Timothy J, Hackett, L Peter, Ilett, Kenneth F
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014565/
https://ncbi.nlm.nih.gov/pubmed/11736879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2001.01506.x
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