Endothelin-A receptor antagonist inhibits angiotensin II and noradrenaline in man

AIMS: Endothelin-1 (ET-1) is a potent vasoconstrictor produced by the vascular endothelium. The interactions of ET with the mediators of the sympathetic nervous system and the renin-angiotensin-system in humans are unclear. METHODS: We studied the effects of the ET(A)-selective antagonist BQ-123 and...

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Bibliographic Details
Main Authors: Wenzel, R R, Rüthemann, J, Bruck, H, Schäfers, R F, Michel, M C, Philipp, Th
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2001
Subjects:
Pharmacodynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014518/
https://ncbi.nlm.nih.gov/pubmed/11488771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01422.x
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