Influence of β-adrenoceptor antagonists on the pharmacokinetics of rizatriptan, a 5-HT(1B/1D) agonist: differential effects of propranolol, nadolol and metoprolol

AIMS: Patients with migraine may receive the 5-HT(1B/1D) agonist, rizatriptan (5 or 10 mg), to control acute attacks. Patients with frequent attacks may also receive propranolol or other β-adrenoceptor antagonists for migraine prophylaxis. The present studies investigated the potential for pharmacok...

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Main Authors: Goldberg, Michael R, Sciberras, David, De Smet, Marina, Lowry, Richard, Tomasko, Lisa, Lee, Yih, Olah, Timothy V, Zhao, Jamie, Vyas, Kamlesh P, Halpin, Rita, Kari, Prasad H, James (deceased), Ian
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2001
Assuntos:
Drug Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014502/
https://ncbi.nlm.nih.gov/pubmed/11453892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01417.x
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