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Increased oral ganciclovir bioavailability in HIV-infected patients with chronic diarrhoea and wasting syndrome—a population pharmacokinetic study

AIMS: Despite a lack of data, the antiviral agent ganciclovir is not indicated in AIDS patients with diarrhoea because of its presumed poor oral bioavailability. To assess the effect of diarrhoea on ganciclovir intestinal absorption, we conducted a pharmacokinetic study in 42 HIV-infected patients c...

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Bibliografiske detaljer
Main Authors: Mouly, Stéphane, Aymard, Guy, Tillement, Jean-Paul, Caulin, Charles, Bergmann, Jean-Francois, Urien, Saik
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014490/
https://ncbi.nlm.nih.gov/pubmed/11422015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01389.x
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