The effect of fluconazole on ritonavir and saquinavir pharmacokinetics in HIV-1-infected individuals

AIMS: To study the effect of fluconazole on the steady-state pharmacokinetics of the protease inhibitors ritonavir and saquinavir in HIV-1-infected patients. METHODS: Five subjects treated with saquinavir and three with ritonavir received the protease inhibitor alone (saquinavir 1200 mg three times...

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Autors principals: Koks, C H W, Crommentuyn, K M L, Hoetelmans, R M W, Burger, D M, Koopmans, P P, Mathôt, R A A, Mulder, J W, Meenhorst, P L, Beijnen, J H
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2001
Matèries:
Short Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014488/
https://ncbi.nlm.nih.gov/pubmed/11422025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01409.x
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