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Simultaneous administration of a cocktail of markers to measure renal drug elimination pathways: absence of a pharmacokinetic interaction between fluconazole and sinistrin, p-aminohippuric acid and pindolol

AIMS: Previous studies suggest that estimated creatinine clearance, the conventional measure of renal function, does not adequately reflect changes in renal drug handling in some patients, including the immunosuppressed. The aim of this study was to develop and validate a cocktail of markers, to be...

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Main Authors: Gross, A S, McLachlan, A J, Minns, I, Beal, J B, Tett, S E
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014485/
https://ncbi.nlm.nih.gov/pubmed/11422014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2001.01390.x
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