A placebo-controlled study examining the effect of allopurinol on heart rate variability and dysrhythmia counts in chronic heart failure

AIMS: Allopurinol improves endothelial function in chronic heart failure by reducing oxidative stress. We wished to explore if such an effect would attenuate autonomic dysfunction in CHF in line with many other effective therapies in CHF. METHODS: We performed a prospective, randomized, double-blind...

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Main Authors: Shehab, Abdullah M A, Butler, Robert, MacFadyen, Robert J, Struthers, Allan D
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014457/
https://ncbi.nlm.nih.gov/pubmed/11318768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2001.01361.x
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