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Induction by agrin of ectopic and functional postsynaptic-like membrane in innervated muscle

Two factors secreted from the nerve terminal, agrin and neuregulin, have been postulated to induce localization of the acetylcholine receptors (AChRs) to the subsynaptic membrane in skeletal muscle fibers. The principal function ascribed to neuregulin is induction of AChR subunit gene expression and...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Jones, G., Meier, T., Lichtsteiner, M., Witzemann, V., Sakmann, B., Brenner, H. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1997
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20144/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122251/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2654
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