Pharmacokinetic-pharmacodynamic evaluation of ceftazidime continuous infusion vs intermittent bolus injection in septicaemic melioidosis

AIMS: Experimental studies have suggested that constant intravenous infusion would be preferable to conventional intermittent bolus administration of beta-lactam antibiotics for serious Gram-negative infections. Severe melioidosis (Burkholderia pseudomallei infection) carries a mortality over 40% de...

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Main Authors: Angus, B J, Smith, M D, Suputtamongkol, Y, Mattie, H, Walsh, A L, Wuthiekanun, V, Chaowagul, W, White, N J
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2000
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Republication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014399/
https://ncbi.nlm.nih.gov/pubmed/10930972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2000.00179.x
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