Failure to respond to treatment with typical antipsychotics is not associated with CYP2D6 ultrarapid hydroxylation

AIMS: To investigate whether or not there is a correlation between failure to respond to typical antipsychotics and CYP2D6 ultrarapid metaboliser status. METHODS: CYP2D6 phenotype (metaboliser status) was assigned following genotyping for gene duplication, as well as for the CYP2D6*3, CYP2D6*4, and...

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Autori principali: Aitchison, Katherine J, Munro, Janet, Wright, Padraig, Smith, Shulabade, Makoff, Andrew J, Sachse, Christoph, Sham, Pak C, Murray, Robin M, Collier, David A, Kerwin, Robert W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1999
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014339/
https://ncbi.nlm.nih.gov/pubmed/10510151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00006.x
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