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Substance P-induced vasodilatation is mediated by the neurokinin type 1 receptor but does not contribute to basal vascular tone in man
AIMS: Following intravenous administration of its prodrug, L-758,298, we assessed the pharmacodynamics of L-754,030, a novel and highly selective NK(1) receptor antagonist, by examining systemic haemodynamics and the blood flow responses to intra-arterial substance P infusion. METHODS: Sixteen healt...
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Main Authors: | , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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Blackwell Science Inc
1999
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014330/ https://ncbi.nlm.nih.gov/pubmed/10510144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00017.x |
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