Dietary caffeine as a probe agent for assessment of cytochrome P4501A2 activity in random urine samples

AIMS: To validate the use of randomly collected urine samples for assessment of cytochrome P4501A2 (CYP1A2) activity based on dietary caffeine (caffeine metabolic ratio, MR(caff)), and to relate the MR(caff) to caffeine intake and smoking habits in a larger group of individuals. METHODS: Nineteen he...

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Bibliographic Details
Main Authors: Nordmark, Anna, Lundgren, Stefan, Cnattingius, Sven, Rane, Anders
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 1999
Subjects:
Drug Disposition
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014237/
https://ncbi.nlm.nih.gov/pubmed/10233204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00918.x
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