Vasoconstriction in human isolated middle meningeal arteries: determining the contribution of 5-HT(1B)- and 5-HT(1F)-receptor activation

AIMS: Sumatriptan is a 5-HT(1B/1D)-receptor agonist which also has affinity for 5-HT(1F)-receptors. The vasoconstrictor effects of sumatriptan are thought to be 5-HT(1B)-receptor mediated and these receptors have been shown to be expressed in human cranial blood vessels. However, in the same tissue...

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Detalhes bibliográficos
Main Authors: Razzaque, Z, Heald, M A, Pickard, J D, Maskell, L, Beer, M S, Hill, R G, Longmore, J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014192/
https://ncbi.nlm.nih.gov/pubmed/10073743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00851.x
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