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The influence of CYP2D6 activity on the kinetics of propafenone enantiomers in Chinese subjects

AIMS: To determine role of CYP2D6 activity in the pharmacokinetics of propafenone (PPF) enantiomers in native Chinese subjects. METHODS: Sixteen extensive metabolizers (EMs) and one poor metabolizer (PM), whose phenotype had been previously assessed with dextromethorphan metabolic phenotyping, were...

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Detalhes bibliográficos
Main Authors: Cai, W M, Chen, B, Cai, M H, Chen, Y, Zhang, Y D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014184/
https://ncbi.nlm.nih.gov/pubmed/10336580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00932.x
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