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Endothelium-independent constriction of isolated, pressurized arterioles by N(ω)-nitro-L-arginine methyl ester (L-NAME)

BACKGROUND AND PURPOSE: Nitric oxide synthase (NOS) inhibitors cause vasoconstriction in pressurized arterioles with myogenic tone. This suggests either tonic production of NO modulates myogenic tone or a direct, NOS-independent effect of the NOS inhibitors. The nature of the contractile effect of t...

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Autori principali: Murphy, T V, Kotecha, N, Hill, M A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013995/
https://ncbi.nlm.nih.gov/pubmed/17471179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707262
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