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Antileukoproteinase protects against hepatic inflammation, but not apoptosis in the response of D-galactosamine-sensitized mice to lipopolysaccharide

BACKGROUND AND PURPOSE: There is major evidence for the strong bi-directional interrelation of parenchymal cell apoptosis and leukocyte accumulation and inflammation in acute liver injury. Therefore, the aim of this in vivo study was to investigate the anti-apoptotic and anti-inflammatory potential...

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Detalhes bibliográficos
Main Authors: Eipel, C, Kidess, E, Abshagen, K, LeMinh, K, Menger, M D, Burkhardt, H, Vollmar, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013978/
https://ncbi.nlm.nih.gov/pubmed/17420780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707230
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