Non-steroidal anti-inflammatory drugs increase insulin release from beta cells by inhibiting ATP-sensitive potassium channels

BACKGROUND AND PURPOSE: Some non-steroidal anti-inflammatory drugs (NSAIDs) incidentally induce hypoglycemia, which is often seen in diabetic patients receiving sulphonylureas. NSAIDs influence various ion channel activities, thus they may cause hypoglycemia by affecting ion channel functions in ins...

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Detalhes bibliográficos
Main Authors: Li, J, Zhang, N, Ye, B, Ju, W, Orser, B, Fox, J E M, Wheeler, M B, Wang, Q, Lu, W-Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013967/
https://ncbi.nlm.nih.gov/pubmed/17435793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707259
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