Melatonin inhibits nitric oxide production by microvascular endothelial cells in vivo and in vitro

BACKGROUND AND PURPOSE: We have previously shown that melatonin inhibits bradykinin-induced NO production by endothelial cells in vitro. The purpose of this investigation was to extend this observation to an in vivo condition and to explore the mechanism of action of melatonin. EXPERIMENTAL APPROACH...

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Bibliographic Details
Main Authors: Silva, C L M, Tamura, E K, Macedo, S M D, Cecon, E, Bueno-Alves, L, Farsky, S H P, Ferreira, Z S, Markus, R P
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2007
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013957/
https://ncbi.nlm.nih.gov/pubmed/17375079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707225
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