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Endothelin-1 activates ETA receptors to cause reflex scratching in BALB/c mice

BACKGROUND AND PURPOSE: Endothelin-1 (ET-1) is present in murine and human skin and causes itch (pruritus) when injected in humans. This behavioural study examined the scratch reflex evoked by ET-1 in mice. EXPERIMENTAL APPROACH: An automated detector was used to determine whether ET-1 causes reflex...

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Detalhes bibliográficos
Main Authors: McQueen, D S, Noble, M A H, Bond, S M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013956/
https://ncbi.nlm.nih.gov/pubmed/17351652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707216
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