Characterization of [(35)S]t-butylbicyclophosphorothionate ([(35)S]TBPS) binding to GABA(A) receptors in postmortem human brain

BACKGROUND AND PURPOSE: The aim of the present study was to determine whether binding of [(35)S]t-butylbicyclophosphorothionate ([(35)S]TBPS) to the convulsant binding site of GABA(A) receptors in human postmortem brain samples can be used as an in vitro index of the functional activation of these r...

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Bibliographic Details
Main Authors: Atack, J R, Ohashi, Y, McKernan, R M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2007
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013908/
https://ncbi.nlm.nih.gov/pubmed/17339834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707186
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