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Inhibitors of phosphodiesterase 5 (PDE 5) inhibit the nerve-induced release of nitric oxide from the rabbit corpus cavernosum

BACKGROUND AND PURPOSE: Nitrergic neurons are important for erectile responses in the corpus cavernosum and impaired signalling results in erectile dysfunction, today treated successfully by oral administration of the selective phosphodiesterase 5 (PDE 5) inhibitors sildenafil, tadalafil and vardena...

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Main Authors: Hallén, K, Wiklund, N P, Gustafsson, L E
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013895/
https://ncbi.nlm.nih.gov/pubmed/17179943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706991
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