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Intraplantar PGE(2) causes nociceptive behaviour and mechanical allodynia: the role of prostanoid E receptors and protein kinases

BACKGROUND AND PURPOSE: Receptor subtypes involved in PGE(2)-induced nociception are still controversial. The present study investigated the prostanoid E receptor (EP) subtypes and the protein kinase (PK) pathways involved in the nociception induced by PGE(2) injection in the mouse paw. EXPERIMENTAL...

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Detalhes bibliográficos
Main Authors: Kassuya, C A L, Ferreira, J, Claudino, R F, Calixto, J B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013868/
https://ncbi.nlm.nih.gov/pubmed/17310141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707149
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