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The importance of baseline in identifying 8-OH-DPAT-induced effects on prepulse inhibition in rats

BACKGROUND AND PURPOSE: Prepulse inhibition (PPI) of the acoustic startle response is a model of sensorimotor gating which is disrupted in schizophrenia and other mental illnesses. We and others have shown that treatment with the 5-hydroxytryptamine-1A (5-HT(1A)) receptor agonist, 8-OH-DPAT, disrupt...

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Bibliografiska uppgifter
Huvudupphovsmän: Gogos, A, van den Buuse, M
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013865/
https://ncbi.nlm.nih.gov/pubmed/17279088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707148
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