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Study on the cyclic GMP-dependency of relaxations to endogenous and exogenous nitric oxide in the mouse gastrointestinal tract

BACKGROUND AND PURPOSE: cGMP mediates nitrergic relaxations of intestinal smooth muscle, but several studies have indicated that cGMP-independent mechanisms may also be involved. We addressed this contention by studying the effect of ODQ and NS2028, specific inhibitors of soluble guanylate cyclase,...

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Bibliografiske detaljer
Main Authors: De Man, J G, De Winter, B Y, Herman, A G, Pelckmans, P A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013844/
https://ncbi.nlm.nih.gov/pubmed/17115067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706964
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