Rapid desensitization of somatodendritic 5-HT(1A) receptors by chronic administration of the high-efficacy 5-HT(1A) agonist, F13714: a microdialysis study in the rat

BACKGROUND AND PURPOSE: Desensitization of somatodendritic 5-HT(1A) receptors is involved in the mechanism of action of several antidepressants, but the rapidity of this effect and the amount of agonist stimulation needed are unclear. We evaluated the capacity of the high-efficacy 5-HT(1A) agonist,...

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Detalhes bibliográficos
Main Authors: Assié, M-B, Lomenech, H, Ravailhe, V, Faucillon, V, Newman-Tancredi, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013794/
https://ncbi.nlm.nih.gov/pubmed/16921393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706859
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