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Genetic Background Modifies Inner Ear and Eye Phenotypes of Jag1 Heterozygous Mice
Mice heterozygous for missense mutations of the Notch ligand Jagged1 (Jag1) exhibit head-shaking behavior indicative of an inner ear vestibular defect. In contrast, mice heterozygous for a targeted deletion of the Jag1 gene (Jag1(del1)) do not demonstrate obvious head-shaking behavior. To determine...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Copyright © 2007 by the Genetics Society of America
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2013712/ https://ncbi.nlm.nih.gov/pubmed/17890364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.075960 |
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