Autophagy Genes unc-51 and bec-1 Are Required for Normal Cell Size in Caenorhabditis elegans

Here we show that in the nematode Caenorhabditis elegans mutational inactivation of two autophagy genes unc-51/atg1 and bec-1/atg6/beclin1 results in small body size without affecting cell number. Furthermore, loss-of-function mutations in unc-51 and bec-1 suppress the giant phenotype of mutant anim...

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Main Authors: Aladzsity, István, Tóth, Márton L., Sigmond, Tímea, Szabó, Emese, Bicsák, Bertalan, Barna, János, Regős, Ágnes, Orosz, László, Kovács, Attila L., Vellai, Tibor
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2007 by the Genetics Society of America 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013693/
https://ncbi.nlm.nih.gov/pubmed/17890369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.075762
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