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In vivo activation of the cystic fibrosis transmembrane conductance regulator mutant ΔF508 in murine nasal epithelium

The gene causing cystic fibrosis (CF) encodes the CF transmembrane conductance regulator (CFTR), a cAMP-regulated chloride channel. Mutations in this gene result in reduced transepithelial chloride permeability across tissues affected in CF. Consequently, restoring chloride permeability to these tis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kelley, Thomas J., Thomas, Kirk, Milgram, Laura J. H., Drumm, Mitchell L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences of the USA 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC20135/
https://ncbi.nlm.nih.gov/pubmed/9122242
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