Collagenase inhibition in colonic mucosa by proteinase inhibitors.

The effect of proteinase inhibitors on collagenase activity in rabbit colonic mucosa, both in vitro and in vivo, has been measured by a tissue culture method. Aprotinin, when applied to colonic explants at doses of 20 and 40 KIU, significantly reduced the lytic activity by 97.3% and 99.1% respective...

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Bibliographic Details
Main Authors: Lewin, M. R., Chowcat, N. L., Jayaraj, A. P., Boulos, P. B.
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013044/
https://ncbi.nlm.nih.gov/pubmed/2427100
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