Dose-response relationships in chemical carcinogenesis: renal mesenchymal tumours induced in the rat by single dose dimethylnitrosamine.

A single intraperitoneal dose of dimethylnitrosamine (DMN) given to weanling rats after 3 days' treatment with a protein-free diet results in the induction of renal mesenchymal tumours, the incidence of which is related to the dose of DMN in a sigmoid dose-response curve. The number of tumours...

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Main Authors: Driver, H. E., White, I. N., Butler, W. H.
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013020/
https://ncbi.nlm.nih.gov/pubmed/3580278
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