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HIV Protease-Activated Molecular Switches Based on Beta-Glucuronidase and Alkaline Phosphatase

Our long-term goal is to direct the evolution of novel protease variants. To this end we have engineered a new type of protease-activated reporter enzyme. Many protease-activated enzymes evolved in nature, but the introduction of novel regulatory mechanisms into normally unregulated enzymes poses a...

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Autors principals: O’Loughlin, T.L., Matsumura, I.
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2012946/
https://ncbi.nlm.nih.gov/pubmed/16724922
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