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Stable Expression of hom-1-thrB in Corynebacterium glutamicum and Its Effect on the Carbon Flux to Threonine and Related Amino Acids

The hom-1-thrB operon encodes homoserine dehydrogenase resistant to feedback inhibition by L-threonine and homoserine kinase. Stable expression of this operon has not yet been attained in different Corynebacterium glutamicum strains. We studied the use of chromosomal integration and of a low-copy-nu...

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Auteurs principaux: Reinscheid, Dieter J., Kronemeyer, Wolfgang, Eggeling, Lothar, Eikmanns, Bernhard J., Sahm, Hermann
Format: Artigo
Langue:Inglês
Publié: 1994
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC201279/
https://ncbi.nlm.nih.gov/pubmed/16349146
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