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Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis

Genetically obese fatty/fatty rats and obese/obese mice exhibit increased sensitivity to endotoxin hepatotoxicity, quickly developing steatohepatitis after exposure to low doses of lipopolysaccharide (LPS). Among obese animals, females are more sensitive to endotoxin liver injury than males. LPS ind...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yang, Shi Qi, Lin, Hui Zhi, Lane, M. Daniel, Clemens, Mark, Diehl, Anna Mae
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences of the USA 1997
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC20127/
https://ncbi.nlm.nih.gov/pubmed/9122234
Tagiau: Ychwanegu Tag
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