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Is heterogeneous expression of HLA-dr antigens and CEA along with DNA-profile variations evidence of phenotypic instability and clonal proliferation in human large bowel carcinomas?

Epithelial expression of HLA-DR determinants and CEA was studied by immunofluorescence in tissue sections from 33 large bowel carcinomas of different histological grade and clinico-pathological stage; flow cytometric DNA measurements were performed in 31 of the tumours. Well-differentiated carcinoma...

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Bibliographic Details
Main Authors: Rognum, T. O., Brandtzaeg, P., Thorud, E.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1983
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2011506/
https://ncbi.nlm.nih.gov/pubmed/6354239
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