Ultrastructural and biochemical observations on the effect of 4-hydroxyanisole plus tyrosinase on normal human melanocytes and keratocytes in tissue culture.

Cultures of melanocytes and keratocytes were exposed to 15 micrograms ml-1 tyrosinase and 4-hydroxyanisole (4-OHA) 5 X 10(-4) M to 5 X 10(-2) M for 1 to 24 h. No damage was suffered by either cell below 5 X 10(-3) M 4-OHA for 6 h, but higher concentrations and longer exposures extensively damaged bo...

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Главные авторы: Breathnach, A., Robins, E., Ethridge, L., Bhasin, Y., Gallagher, S., Passi, S., Nazzaro-Porro, M.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1983
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2011350/
https://ncbi.nlm.nih.gov/pubmed/6407506
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