Inhibition of Gene Expression in Escherichia coli by Antisense Phosphorodiamidate Morpholino Oligomers

Antisense phosphorodiamidate morpholino oligomers (PMOs) were tested for the ability to inhibit gene expression in Escherichia coli. PMOs targeted to either a myc-luciferase reporter gene product or 16S rRNA did not inhibit luciferase expression or growth. However, in a strain with defective lipopol...

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Bibliographische Detailangaben
Hauptverfasser: Geller, B. L., Deere, J. D., Stein, D. A., Kroeker, A. D., Moulton, H. M., Iversen, P. L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Mechanisms of Action: Physiological Effects
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC201127/
https://ncbi.nlm.nih.gov/pubmed/14506035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.10.3233-3239.2003
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