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Accumulation of 125I-labelled thiouracil and propylthiouracil in murine melanotic melanomas.

We have shown that thioamides are incorporated as false precursors into melanin during its synthesis. To be clinically useful in the diagnosis or therapy of melanotic melanomas, they would have to be tagged with an appropriate isotope or possibly a cytotoxic moiety. 125I-Thiouracil (125I-TU) is here...

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Main Authors: Larsson, B., Olander, K., Dencker, L., Holmqvist, L.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 1982
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2011190/
https://ncbi.nlm.nih.gov/pubmed/7138763
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