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Effect of ICRF-187 on doxorubicin-induced myocardial effects in the mouse and guinea pig.

ICRF-187 was tested for cardioprotective activity in doxorubicin-treated mice and guinea pigs. Pretreatment with i.p. ICRF-187 caused a significant decrease in the indicence of i.v. doxorubicin-induced myocardial histological damage in the mouse. I.p. ICRF-187 did not, however, reduce the effect of...

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Detalhes bibliográficos
Main Authors: Perkins, W. E., Schroeder, R. L., Carrano, R. A., Imondi, A. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2011185/
https://ncbi.nlm.nih.gov/pubmed/6814473
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