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The Urokinase Receptor Can Be Induced by Borrelia burgdorferi through Receptors of the Innate Immune System

Monocytic cells exposed to Borrelia burgdorferi, through unknown receptors, overexpress the urokinase receptor (uPAR), a key mediator of the plasminogen activation system. We show that combined blockade of CD14 and TLR2 causes a significant inhibition of B. burgdorferi-induced uPAR in Mono Mac 6 (MM...

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Detalhes bibliográficos
Main Authors: Coleman, James L., Benach, Jorge L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC201106/
https://ncbi.nlm.nih.gov/pubmed/14500474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.10.5556-5564.2003
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