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Must initiators come first? Tumorigenic and carcinogenic effects on skin of 3-methylcholanthrene and TPA in various sequences.

Groups of hairless mice were treated with 4 skin applications of 470 nmol 3-methylcholanthrene (MCA) in benzene and 4 of 20 nmol 12-O-tetradecanoylphorbol-13-acetate (TPA) in various sequences, twice a week, together and separately. Three days after the last application, cell kinetic investigations...

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Bibliografiske detaljer
Main Authors: Iversen, O. H., Iversen, U. M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1982
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2011048/
https://ncbi.nlm.nih.gov/pubmed/7093124
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