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Effect of clinical levels of misonidazole on the response of tumour and normal tissues in the mouse to alkylating agents.

Experiments were carried out to determine whether the enhancement of alkylating-agent cytotoxicity seen after large single doses of misonidazole (MISO) in mouse tumours can also be achieved by prolonged exposure to low MISO levels similar to those which can be tolerated clinically. The level in mous...

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Détails bibliographiques
Auteurs principaux: Brown, J. M., Hirst, D. G.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1982
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2011020/
https://ncbi.nlm.nih.gov/pubmed/7082556
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