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Lymphotoxin-β receptor signaling complex: Role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor κB

The binding of heterotrimeric lymphotoxin, LTα(1)β(2), to the LTβ receptor (LTβR), a member of the tumor necrosis factor receptor (TNFR) superfamily, induces nuclear factor κB (NF-κB) activation and cell death in HT29 adenocarcinoma cells. We now show that treatment with LTα(1)β(2) or agonistic LTβR...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: VanArsdale, Todd L., VanArsdale, Sammee L., Force, Walker R., Walter, Barbara N., Mosialos, George, Kieff, Elliott, Reed, John C., Ware, Carl F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20110/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122217/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2460
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