Host Resistance of CD18 Knockout Mice against Systemic Infection with Listeria monocytogenes

Mice with targeted mutations of CD18, the common β2 subunit of CD11/CD18 integrins, have leukocytosis, impaired transendothelial neutrophil emigration, and reduced host defense to Streptococcus pneumoniae, a gram-positive extracellular bacterium. Previous studies using blocking monoclonal antibodies...

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Autors principals: Wu, Huaizhu, Prince, Joseph E., Brayton, Cory F., Shah, Chirayu, Zeve, Daniel, Gregory, Stephen H., Smith, C. Wayne, Ballantyne, Christie M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Host Response and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC201099/
https://ncbi.nlm.nih.gov/pubmed/14500519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.10.5986-5993.2003
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